20+ Million Readerbase
Indexed In
  • RefSeek
  • Hamdard University
  • EBSCO A-Z
  • Publons
  • Google Scholar
Share This Page
Recommended Webinars & Conferences

4th Annual Summit on Cardiology and Heart Diseases

Toronto, Canada

2nd International Congress on Heart

Singapore, Singapore
Journal Flyer
Flyer image

Naga Bharathi M

Department of Pharmacology, Sri Vasavi Institute of Pharmaceutical Sciences, Pedatadepalli, Tadepalligudem, Andhra Pradesh, India

Publications
  • Research Article   
    Comparative Evaluation of In Vitro Thrombolytic Activity of Four Medicinal Plants
    Author(s): Naga Bharathi M*, Devi Sirisha G, Manoj kumar M, Sai Kanaka durga L, Harshitha K, Satyasree D and Srinivas K

    Thrombolytic drugs are mainly used for the treatment of myocardial infarction, which occurs due to thrombus formation and causes tissue necrosis. Currently plasminogen activator (t-PA), streptokinase, urokinase are used, but the major drawback was adverse effects like hemorrhage, allergic reactions and lack of specificity.The present study was aimed to investigate in vitro thrombolytic activity of methanolic and aquoes extract of Phyllanthus niruri, Nyctanthes arbor- tristis, Syzygium cumini and Clome gynandra, where streptokinase and water were used as positive and negative control. Among the medicinal plants Nyctanthes arbor- tristis(aqueous) extract exhibited highest thrombolytic activity by clot lysis of 14.2%, followed by Cleome gynandra(aqueous) extract with 7.7% of clot lysis and Phyllanthus niruri(methanol) extract with 6.7% clot lysis when compared with S.. Read More»

    DOI: 10.35248/2572-9462.22.8.196

    Abstract HTML PDF

bellicon