Indexed In
- Open J Gate
- Genamics JournalSeek
- JournalTOCs
- Ulrich's Periodicals Directory
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Publons
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Masaki Okumura
Department of Applied Life Sciences, Sojo University, Kumamoto, Japan
Publications
-
Research Article
Growth Suppression of Triple-Negative Breast Cancer Cells by the Photodynamic Therapy Effect of Hybrid Liposomes Containing Indocyanine Green
Author(s): Masaki Okumura, Hinano Otsuka, Junna Takai, Koichi Goto, Yoko Matsumoto and Hideaki Ichihara*
The growth suppression effects by Photodynamic Therapy (PDT) of Hybrid Liposomes (HL/ICG) composed of 89 mol% L-α-Dimyristoylphosphatidylcholine (DMPC), and 10 mol% polyoxyethylene(25) dodecyl ether (C12(EO)25) including 1 mol% Indocyanine Green (ICG) was investigated for mouse triple negative breast cancer (4T1-Luc) cells. A clear HL and HL/ICG solution with a hydrodynamic diameter of 100 nm remained stable for four weeks. A significant decrease in 4T1-Luc cell viability was observed following PDT with HL/ICG. Fluorescence microscopy confirmed the accumulation of HL/ICG in 4T1-Luc cells. An increase in fluorescence intensity, indicating Reactive Oxygen Species (ROS) production in 4T1-Luc cells with PDT of HL/ICG, was observed using both fluorescence microscopy and flow cytometry... View more»