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Maria Beihaghi
Departmentof Biology, The University of Georgia, Tbilisi, Georgia
Publications
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Research Article
Diagnosis of Colon Cancer Using LncRNA ROR Gene Biomarker
Author(s): Maria Beihaghi*, Reza Sahebi, Mohammad Reza Beihaghi, Raheleh Khosravi Nessiani and Majedeh Ramian
Colorectal Cancer (CRC), which is one of the most commonly diagnosed cancers worldwide, threatens human health. Since the pathological mechanism of CRC is not entirely understood, there are many challenges in preventing, diagnosing, and treating this disease. Long non-coding RNAs (LncRNAs) have recently gained attention due to their potential role in various stages of CRC formation, invasion, and progression, including regulation of molecular signaling pathways, apoptosis, autophagy, angiogenesis, tumor metabolism, immune responses, cell cycle, and Epithelial Mesenchymal Transition (EMT). The role of long non-coding RNA Regulator of Reprogramming (ROR) in cellular reprogramming has been studied in this research. After extracting and preparing RNA from 100 cancerous and 100 non-cancerous tissues, the expression changes of Linc-ROR and all samples were analyzed with the Real time PCR te.. View more»