Department of Radiology, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho Itabashi-ku, Tok, Japan
Review Article
Sinusoidal obstruction syndrome/veno-occlusive disease in adult patients after hematopoietic stem cell transplantation: a review of diagnostic accuracy of liver stiffness measurement by elastography
Author(s): Kazumi Fujioka*
The recent European Society for Blood and Marrow Transplantation (EBMT) criteria for diagnosis of Sinusoidal Obstruction Syndrome/Veno-Occlusive disease (SOS/VOD) provided a new classification of “probable” SOS/VOD to improve early diagnosis and ensure prompt therapy with defibrotide. Transient Elastography (TE) and Shear Wave Elastography (SWE) have emerged for early and accurate diagnosis of SOS/VOD after Hematopoietic Stem Cell Transplantation (HSCT). In this review, the author outlined the current knowledge and trends of SOS/VOD in adult patients after HSCT for diagnostic accuracy of Liver Stiffness Measurement (LSM) by elastography. The MEDLINE, PubMed and EMBASE data-bases were systematically accessed for studies using elastography in adult patients after HSCT. In addition, the new biomarker studies for endothelial damage such as VOD check and Circulating Endothelial.. View more»