Department of Dermatology, Warsaw Medical University, Warszawa, Poland
Review Article
Accumulation of Pigment Particles Used in Tattooing in Human Skin-Results of Histological Studies
Author(s): Anna Charuta*, Agnieszka Paziewska, Iwona Luszczewska-Sierakowska, Marta Gajewska Justyna Olszewska, Michalina Kosowska and Agata Wawrzyniak
The reports of the dangers of tattoos and the observed side effects have increased interest in the toxicity of tattoo pigments. The effects of tattoo pigments on skin homeostasis remain largely unknown. This is why research on the accumulation of pigment particles in the layers and cells of the skin (macrophages, fibroblasts) is so important. The main aim was to analyze which cells phagocyte tattoo ink in human skin. The accumulation of pigment particles used in tattooing in individual skin layers and in skin cells such as macrophages and fibroblasts was analyzed. The test material was human skin fragments with a tattoo, measuring 3 × 3 cm (including subcutaneous tissue), taken from human cadavers from the deltoid region, thorax, abdomen and the lateral aspect of the arm. Immunohistochemical staining was performed to identify Leukocyte Common Antigen (LCA) leukocytes without T a.. View more»