Department of Ophthalmology, Boston Medical Center/Boston University School of Medicine, Boston, MA 02118, USA
He is currently working as a Professor in the Department of Ophthalmology, Boston Medical Center/Boston University School of Medicine, Boston, MA 02118, USA. His research interests include Ophthalmology. He is serving as an editorial member and reviewer of several international reputed journals. He has successfully completed his Administrative responsibilities. He has authored many research articles/books related to Ophthalmology.
Research Article
Ologen versus Mitomycin-C for Trabeculectomy in a Predominantly African American Population
Author(s): Kenneth C Fan*, Howard Guan, Meenakshi Chaku, Manishi A Desai and Babak Eliassi-Rad
Objective: To investigate the efficacy and safety of the collagen-based Ologen implant as an adjuvant therapy in trabeculectomy as compared to mitomycin-C (MMC) in a predominantly African American patient population.
Methods: This study was a retrospective review of 54 eyes of 50 primary open angle glaucoma patients who underwent trabeculectomy with either MMC or Ologen. 16 eyes were included in the MMC group and 38 in the Ologen group. Primary outcomes included treatment success (as defined by target IOP <21 mmHg, IOP reduction >20) both qualified (with and without medications) and unqualified (without medication), overall IOP reduction, and reduction of number of medications as compared to pre-operative state. Secondary outcomes included evaluation of treatment adverse events.
Results: No significant differ.. View more»