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Doaa Mahmoud Alzayat
Department of Radiation Oncology, Ayadi Almostakbal Oncology Hospital, Alexandria, Egypt
Publications
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Research Article
Outcomes, toxicities and dosimetric comparison of different hypofractionated Intensity modulated Radiotherapy techniques for treatment of Localized Prostate Cancer
Author(s): Sherif Elzawawy*, Taha Ismail Mohamed Hawala, Doaa Mahmoud Alzayat and Ramadan Hammam
Background: conventional fractionation IMRT is the standard treatment for localized prostate cancer patients. The objectives of this study were to evaluate safety and efficacy of Hypofractionated radiotherapy with dosimetric comparison between 5, 7 and 9 IMRT fields. Methods: Low or intermediate risk patients included. Three sets of Inverse planning IMRT were carried out (5, 7 and 9 Fields) for each patient with total dose of 70 Gy/28 fractions. Results: 20 patients were recruited. Regarding PTV coverage, there were no statistically significant differences regarding D2%, D5%, D50%, D95%, D98%, Dmax, Dmin, Dmean, conformity index, homogeneity index, between 5, 7 or 9 Fields. (p=0.25, 0.38, 0.969, 0.057, 0.294, 0.057, 0.517, 0.969, 0.313 and 0.969, respectively). Statistically significant difference regardi.. View more»