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Adrean Sean D
Retinal Consultants of Orange County, Fullerton, USA
Biography
Ibrahim MM is currently working as Adrean SD, Retinal Consultants of Orange County, Fullerton, USA,His research interests includes Medicine,He has authored of many research articles/books related to Medicine.
Publications
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Review Article
A Comparison of Management Strategies and Treatment Results for Neovascular Age-Related Macular Degeneration with a Focus on the Treat-Extend-Stop Protocol
Author(s): Chaili Siyang and Adrean Sean D*
Neovascular Age-Related Macular Degeneration (nAMD) is a leading cause of blindness, but the management has been revolutionized by anti-vascular endothelial growth factor (anti-VEGF) agents. Three main treatment strategies have been developed to manage nAMD. The first method is fixed interval dosing, a mainstay of randomized clinical trials (RCT), where patients receive treatments on a monthly or bimonthly interval based on the anti-VEGF agent. Shortly thereafter, the pro-re-nata (PRN) method was introduced, where patients were treated as needed based on OCT status, usually preceded by three loading doses. Another method developed was the TreatAnd-Extend regimen (TAE). Patients are treated until a dry macula is obtained and then the time interval between injections is gradually increased, usually by one to two-week intervals. A variation of the TAE protocol, termed TreatExtend-Stop (T.. View more»