Biochemistry & Analytical Biochemistry

Yudan Zhao

Publications

• Research Article
  The Effect of Umbilical Cord Blood Mesenchymal Stem Cells on the Neurological Function and the Expression of Caspase-3 in Cerebral Ischemiareperfusion Rats
  Author(s): Ming Zhang, Xiaomin Hua, Yudan Zhao, Bin Wang and Yujun XiaMing Zhang, Xiaomin Hua, Yudan Zhao, Bin Wang and Yujun Xia
  
  Cerebral infarction, a type of ischemic stroke disease, is a threat to human health. Thrombolytic therapy and brain protection methods have been used to treat cerebral infarction clinically. Recently, cell therapy has become a hotspot. This study aimed to explore the effect of Umbilical Cord Blood Mesenchymal Stem Cells on the neurological function and the expression of caspase-3 in cerebral ischemia-reperfusion rats. Methods: The rat cerebral infarction models were established. The treatment group was injected into 2×106 Umbilical Cord Blood Mesenchymal Stem Cells; Sham-operated group and the control were injected into the same amount of cell culture media. Evaluation of neurological function was performed and the mRNA and protein expression level of caspase-3 was detected using RT-PCR and immunohistochemical method, respectively. Apoptosis ana.. View More»
  DOI: 10.4172/2161-1009.1000170

  Abstract PDF