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Yongping Zhang
Yongping Zhang
China
Publications
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Review Article
The Efficacy and Safety of Bismuth-Based Quadruple Therapy for Helicobacter Pylori Infection: A Meta-Analysis
Author(s): Yongping Zhang, Yifeng Zhou, Qi Zhang, Xiaofeng Zhang and Qiang CaiYongping Zhang, Yifeng Zhou, Qi Zhang, Xiaofeng Zhang and Qiang Cai
Objective: To assess the safety and efficacy of bismuth-based quadruple therapy for Helicobacter pylori (H. pylori) infection. Methods: We searched the PubMed, Cochrane and EMBASE databases updated to January 2015 for randomized controlled trials (RCTs) comparing bismuth-based quadruple therapy (Bismuth quadruple therapy) with non-bismuth standard triple therapy (standard therapy) for H. pylori infection. Literature qualities were assessed using Cochrane assessment system. Meta-analysis was carried out with Stata 11.0 and Review Manager 5.3. Risk ratio (RR) and their 95% confidence interval (95% CI) were computed. Subgroup analysis and sensitivity analysis were performed. Egger’s test was performed to evaluate publication bias among studies. Results: Ten RCTs were eligible and enrolled. In the overall analysis, bismuth quadruple therapy achieved comparable intention-to-treat cur.. View More»
DOI: 10.4172/2153-2435.1000382