Pharmaceutica Analytica Acta

Wing P Chan

Publications

• Research Article
  Using Topical Applications of Tamoxifen and a Combination of Phytonutrients Based on Breast MRI to Inhibit Estrogen-Related Proliferation of Human Breast Tissue
  Author(s): Shoei-Loong Lin, Cheuk-Sing Choy, Wing P Chan and Ting-Kai LeungShoei-Loong Lin, Cheuk-Sing Choy, Wing P Chan and Ting-Kai Leung
  
  Objective: In January of 2013, the National Institute of Health and Clinical Excellence of United Kingdom have announced that taking tamoxifen for five years could reduce breast cancer risk, include positive family history or chronic estrogen and phytoestrogen users. However, routinely oral intake of tamoxifen for breast cancer prophylaxis on high risk women is occasionally difficult because of its potential side effects. The intention of this study is to prove transdermal delivery by using minimal dose of tamoxifen and phytonutrients for breast protection. Methods: We retrospectively studied 2795 breast MRI images from Taiwanese women and classified them as either healthy or unhealthy according to BI-RADS categories. A subgroup of the study patients had received estrogen supplements containing estrogen components or phytoestrogen for at least 3 months. Based on breast MRI analysis, t.. View More»
  DOI: 10.4172/2153-2435.1000281

  Abstract PDF