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Waseem Hassan
Waseem Hassan
Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria,
Santa Maria, CEP 97105-900, RS
Brazil
Publications
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Research Article
Understanding the Mechanism of Antioxidant Potential of Organochalcogens in Rat's Brain Preparation
Author(s): Waseem Hassan, Senthil Narayanaperumal, Matheus M. Santos, Kashif Gul, Imdad Ullah Mohammadzai, Antonio L. Braga, Oscar Dorneles Rodrigues and Joao B. T. RochaWaseem Hassan, Senthil Narayanaperumal, Matheus M. Santos, Kashif Gul, Imdad Ullah Mohammadzai, Antonio L. Braga, Oscar Dorneles Rodrigues and Joao B. T. Rocha
In the quest to explore mechanism of action of organochalcogens a series of them are tested for their structuralactivity relationship using rat’s brain preparation. Dichalcogenides are better anti-oxidants than structurally analogues mono- chalcogenides. Effects of electron donating and withdrawing groups have been explored and explained in detail. We have also proved that structural isomerisation does not influence the anti-oxidant activity of these compounds. .. View More»
DOI: 10.4172/2153-2435.S3-002