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Vikash Kumar
Vikash Kumar
P. D. Memorial College of Pharmacy,
Sector-3A; Sarai Aurnagabad, Bahadurgarh
India
Publications
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Research Article
Newfangled Quantitative Pharmacia (Isradipine) Stratagem: Quality by Design (Qbd) Taguchi Array via Response Surface (L25 Via CCD20) Methodology
Author(s): Vikash Kumar and Rajeev KharbVikash Kumar and Rajeev Kharb
Statistically (L25 via CCD20), a novel array via response surface analytical process was an attempt to develop a quantification of the pharmacies/bulk, Isradipine using organic medium (methanol & chloroform) as solvent. During analysis, the maximum absorption wavelength of model drug was found at lambda max 327nm and also done its recovery via validation further. In the beginning, by using a quality improvement statistically array looms (Taguchi) was generated numerous level/space (s) of the independent variable (A=methanol; B=chloroform & C=ratio of A: B) by performing experimentally (L25 array runs to studied their response to be found the finer spaces). Additionally, a three-dimensional response surfaces strategy [RSM; three dimensional central composite designs (CCD20)] explored variables non-factorial levels which are used as fine. Also, responses quadratic (02nd order) e.. View More»
DOI: 10.4172/2153-2435.1000411