Journal of Pharmacogenomics & Pharmacoproteomics

Trisha O’Moore-Sullivan

Publications

• Review Article
  Insulin Analogues: Reviewing the Pros and Cons in Managing Diabetes Mellitus
  Author(s): Jennifer H. Martin, Anthony Russell, Trisha O’Moore-Sullivan and Johannes B. PrinsJennifer H. Martin, Anthony Russell, Trisha O’Moore-Sullivan and Johannes B. Prins
  
  The issue of planning the timing and dosing of insulin in relation to food is one of the most difficult issues confronting people with diabetes. Recent focus on improving quality of life in this area has focused on developing different modes of administration of insulin thereby avoiding subcutaneous injections and developing new analogues of insulin. Both inhalational and buccal administration technologies have been developed, and have essentially overcome some of the difficult pharmacokinetic issues regarding large peptide molecules, however there remain some clinical problems. Advances in the practicalities of treating insulin have occurred, such as more accurate and less expensive glucometers, new administration alternatives such as implantable pumps, with further developments in the pipeline including islet and gene replacement for Type I disease. However all of these newer op.. View More»
  DOI: 10.4172/2153-0645.1000106

  Abstract PDF