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Review Article
Soluble Epoxide Hydrolase: Potential Target for Inflammation and Inflammation-Driven Cancer
Author(s): Chao Lou, Liping Zhang, Xiaobing Wang, Xiaoping Ma, Cuiyun Qin, Wei Li, Ting Jia, Qing Nan and Rong QiangChao Lou, Liping Zhang, Xiaobing Wang, Xiaoping Ma, Cuiyun Qin, Wei Li, Ting Jia, Qing Nan and Rong Qiang
Arachidonic acid can be catalyzed by three different kind of metabolizing enzyme: cyclooxygenase (COX), lipoxygenase (LOX) and/or cytochrome P450 (CYP), and they produce prostaglandins, monohydroxys, leukotrienes and epoxyeicosanoids respectively. Through the cytochrome P450 pathway, arachidonic acid can be converted to two kinds of eicosanoid acids: epoxyeicosanoids acid (EET) by cytochrome P450 and hydroxyeicosatetraenoic acids (HETEs) formed by CYP α-oxidases. .. View More»
DOI: 10.4172/2157-2518.1000294