Biology and Medicine

Sergej Brankovich Bolevich

Publications

• Research Article
  Free-Radical Processes in Stroke Patients with Vascular Comorbidity
  Author(s): Ekaterina Vladimirovna Silina, Aleksandra Sergeevna Orlova, Sofia Alekseevna Rumyantseva and Sergej Brankovich BolevichEkaterina Vladimirovna Silina, Aleksandra Sergeevna Orlova, Sofia Alekseevna Rumyantseva and Sergej Brankovich Bolevich
  
  Acute oxygen and glucose defi ciency during brain ischemia leads to the inability of neurons producing a suffi cient amount of adenosine triphosphate (ATP) using an oxidative metabolism. Energy defi ciency leads to neuronal death via different mechanisms including oxidative stress. This study aimed to evaluate the changes and main characteristics of free-radical processes in patients with acute stroke and transient ischemic attacks (TIA) in the presence of vascular comorbidity. One hundred forty-one patients with stroke (male—72, mean age—65.4813.44 years) and with a history of cardiovascular diseases (CVD). Free-radical formation was assessed in plasma based on oxidative (chemiluminescence intensity index—basal [CIIb] and zymosan-stimulated [CIIs]) and lipid-peroxidation markers (antiperoxide plasma activity [APA] and malondialdehyde [MDA]). During the follow-up .. View More»
  DOI: 10.4172/0974-8369.1000344

  Abstract PDF