Sana Sarfaraz
Karachi-74600
Pakistan
Research Article
Comparative Evaluation of Hypolipidemic Effects of Ethanolic Extract of Fruit of Piper chaba and Piper nigrum on Albino Rabbits
Author(s): Sana Sarfaraz, Rahila Najam, Iqbal Azhar and Ghulam SarwarSana Sarfaraz, Rahila Najam, Iqbal Azhar and Ghulam Sarwar
Background: One of the main causes of cardiovascular disease is increased cholesterol in the body. Unfortunately the trend of cardiovascular diseases is still very prevalent and no longer specific to adult population.
Objective: The present study was designed to evaluate the effect of ethanolic extract of fruit of Piper chaba and Piper nigrum on lipid profile and to evaluate which extract is more beneficial and could be helpful in treatment of cardiovascular diseases.
Methodology: The study was conducted on albino rabbits weighing 1000 gms-1600 gms. The animals were administered ethanolic extract of Piper chaba 150 mg/kg and Piper nigrum 250 mg/kg which was further diluted in Di methyl sulfoxide (DMSO) and dose was adjusted in ml based on weight of animals. After 7 days dosing animal’s .. View More»
DOI:
10.4172/2090-2697.1000128