Journal of Thrombosis and Circulation: Open Access

Rani S

Publications

• Research Article
  Antibody Titers Study in Group O Blood Donors: Tube and Column Agglutination Techniques
  Author(s): Sood R, Neelima, Kumar D, Kumar T, Kumar V, Rani S and Kumar SSood R, Neelima, Kumar D, Kumar T, Kumar V, Rani S and Kumar S
  
  Background: O blood group transfusions to patients of all blood groups has continued since long. Clinical significance of ABO antibody titre in ABO-I kidney transplantation is well known. Few studies done on group O blood/ apheresis donations, for detecting ABO antibody titers in collected plasma components. The passively acquired antibodies may destroy recipient’s own red cells and tissue grafts, cause acute hemolysis, hemoglobinemia, jaundice, progressive anemia, spontaneous agglutination, positive direct antiglobulin test and increased osmotic fragility of the patient’s red cells. Objective: To evaluate agglutinin levels in group O blood donations. Group O donor population, randomly selected and titrated using tube technique and gel card technique to identify titer levels for Anti A, Anti B, Anti AB antibodies. Both IgM and IgG .. View More»
  DOI: 10.4172/2572-9462.1000104

  Abstract PDF