Journal of Pharmacogenomics & Pharmacoproteomics

Ramón Cacabelos

Publications

• Research Article
  Benefits of Pharmacogenetics in the Management of Hypertension
  Author(s): Clara Torrellas, Juan Carlos Carril and Ramón CacabelosClara Torrellas, Juan Carlos Carril and Ramón Cacabelos
  
  Introduction: Hypertension, suffered by 35% of the population, stands out as the main risk factor for cardiovascular disorders with the highest death rate worldwide. Only a small number of patients with hypertension gets efficient control over blood pressure (BP) with appropriate drug therapy. Pharmacogenetics, as a tool to identify antihypertensive therapeutic response-associated polymorphisms, could help to reduce this problem. Objectives: We present here an epidemiological study of the prevalence of hypertension and its pharmacological treatment to demonstrate the error rate that physicians can commit when the patient´s pharmacogenetic profile is unknown. Method: The sample consisted of 1115 individuals of which 332 met criteria for hypertension. We recorded each patient´s drug prescription prior to thei.. View More»
  DOI: 10.4172/2153-0645.1000126

  Abstract PDF