Journal of Nanomedicine & Nanotechnology

Pilote M

Publications

• Research Article
  Fate and Immunotoxic Effects of Silver Nanoparticles on Rainbow Trout in Natural Waters
  Author(s): Bruneau A, Turcotte P, Pilote M, Gagné F and Gagnon C Bruneau A, Turcotte P, Pilote M, Gagné F and Gagnon C
  
  This study investigates the fate and the effects of silver nanoparticles (AgNPs) in rainbow trout (Oncorhynchus mykiss). Juveniles were exposed to 50 μg/L of AgNPs 20 nm and 1 μg/L of dissolved silver Ag+ (as AgNO3) in three types of water differing in conductivity, pH and organic matter: green water (Saint-Lawrence River), brown water (Ottawa River), and UV-treated and dechlorinated tap water. After a 96 h exposure, chemical analyses were performed on both water samples and fish tissues (liver and gills) and a suite of immune and hepatic biomarkers were also performed on fish.Results demonstrated that brown water with high organic carbon values (7 mg/L), promoted the formation of small AgNP aggregates that were bioaccumulated in fish gills and liver. In fish exposed to AgNPs, immunostimulation and hepatic oxidative stress were obs.. View More»
  DOI: 10.4172/2157-7439.1000290

  Abstract PDF