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Mohammad Nasri
Mohammad Nasri
Afzalipour School of Medicine, Kerman University of Medical Sciences and Health Services,
Pajouhesh Sq., Bistodo Bahman Blvd., Kerman
West Indies
Publications
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Research Article
Polymeric Nanostructures as Colloidal Drug Delivery Systems: Thermosensitive Hydrogels Containing Self-Assembled Micelles
Author(s): Mohammad Nasri and Hossein MirshekarpourMohammad Nasri and Hossein Mirshekarpour
Polymeric nanostructures for drug delivery applications including smart hydrogels and stealth micelles have been developed to overcome many obstacles in the way of timing and targeting the delivery to fulfill therapeutic potentiality of chemicals. The purpose of this investigation is to prepare and characterize novel nanoparticle-based colloidal products composed of biocompatible polymers to use for rate-controlled release and targeted/spatial drug delivery systems, aiming specifically at drug delivery via mucosal routes. We formulated the new products with inert and biocompatible polymers including sodium carboxymethylcellulose (NaCMC) and polysorbates. The synthesis process was performed by heating/cooling method, as a type of physical cross-linking method for producing hydrogel, in three steps to optimize physical and chemical characteristics of the products to mak.. View More»
DOI: 10.4172/2157-7439.1000301