Journal of Carcinogenesis & Mutagenesis

Líria Hiromi Okuda

Publications

• Research Article
  Bovine Papillomavirus Type 1 in Brains of Cattle with a Neurological Syndrome: Pathological and Molecular Study
  Author(s): Claudia Del Fava, Líria Hiromi Okuda, Marta Elisabete Scarelli Vicente, Maria do Carmo Custódio de Souza Hunold Lara, Eliana Monteforte Cassaro Villalobos, Enio Mori, Talita de Paula Silva Moura, Waleska Villas Boas Loiacono, Dirlene Marques Justino and Edviges Maristela PitucoClaudia Del Fava, Líria Hiromi Okuda, Marta Elisabete Scarelli Vicente, Maria do Carmo Custódio de Souza Hunold Lara, Eliana Monteforte Cassaro Villalobos, Enio Mori, Talita de Paula Silva Moura, Waleska Villas Boas Loiacono, Dirlene Marques Justino and Edviges Maristela Pituco
  
  Bovine papillomavirus (BPV) infection is endemic in Brazilian herds. Papillomaviruses are oncogenic, with a trophic response in squamous epithelial and mucosal tissues, and are associated with asymptomatic infections, proliferative benign skin lesions (papillomas), and malignant epithelial lesions (carcinomas). The presence and expression of BPV in the blood of healthy and papillomatosis-affected cattle has been demonstrated. Experimental inoculation of Bovine papillomavirus (BPV) into calf meninges can result in meningiomas and papillomatosis, but it´s not known if its natural infection causes neoplasia and neurological syndrome in cattle. We assessed the frequency of BPV in 300 Central Nervous System (CNS) samples from cattle with neurological syndrome from several Brazilian regions obtained from surveillance of neurological syndrome. Samples were negative for rabies, Neospora.. View More»
  DOI: 10.4172/2157-2518.1000330

  Abstract PDF