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Kang Joon Lee
Kang Joon Lee
Ilsanpaik Hospital,
College of Medicine, 170, Juhwa-ro, Ilsanseo-gu, Goyangsi, Gyeonggi-do, 411-706
Publications
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Research Article
A Voxel-Based Morphometry Study in Alzheimer?s Disease and Mild Cognitive Impairment
Author(s): Hyun Kim, Yo Sup Kim and Kang Joon LeeHyun Kim, Yo Sup Kim and Kang Joon Lee
Objectives: A number of structural magnetic resonance imaging (MRI) studies have demonstrated grey matter (GM) atrophy in subjects with mild cognitive impairment (MCI) and Alzheimer’s disease (AD). We used a voxel-based morphometric (VBM) approach to evaluate the patterns of atrophy in GM in subjects with AD and MCI in comparison to control subjects. Methods: We performed brain MRI with VBM analysis in 53 subjects with AD, 32 subjects with MCI, and 32 normal elderly controls. Results: In the AD group, we found GM atrophy in the left cingulate gyrus, left dorsal posterior cingulate cortex, left inferior temporal gyrus, and right supramarginal gyrus compared to control subjects, and in the right inferior frontal gyrus, right orbitofrontal area, left uncus, left ventral entorhinal cortex, and left inferior temporal .. View More»
DOI: 10.4172/Psychiatry.1000237