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John Souza
John Souza
Australia
Publications
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Research Article
Bio-Active Nano-Diamond Designer Materials and Dentures: From Design to Application
Author(s): V. Tamara Perchyonok, John Souza, Shengmiao Zhang, Desigar Moodley and Sias GroblerV. Tamara Perchyonok, John Souza, Shengmiao Zhang, Desigar Moodley and Sias Grobler
Objective: The present study aims to design functional biomaterials and evaluate performance of nano-diamond: chitosan based bio-active containing PMMA (polymethyl methacrylate) materials towards application in treatment and prevention of denture stomatitis and associated conditions in denture wearers. Methods: The bio-active nano-diamond modified PMMA were prepared by dispersion of the corresponding component in glycerol and acetic acid with the addition of chitosan gelling agent. The release behaviors at physiological pH and also under acidic conditions and stability of the antioxidant-chitosan-nano-diamond were also evaluated. Mechanical performance such as tensile strength and compressive strength were measured as well bio-adhesive studies were investigated in order to assess the suitability of these des.. View More»
DOI: 10.4172/2161-1122.1000344