Biology and Medicine

J. L. Ngondi

Publications

• Research Article
  Antioxidant and Postprandial Glucose-lowering Potential of the Hydroethanolic Extract of Nypa fruticans Seed Mesocarp
  Author(s): Fonkoua Martin, Nguimkeng Signing Boris, Sandeu Ruth Kengne, Tang Eramus Chia, Takuissu Nguemto Guy, Azantsa Kingue Boris Gabin, J. L. Ngondi and Gouado InnocentFonkoua Martin, Nguimkeng Signing Boris, Sandeu Ruth Kengne, Tang Eramus Chia, Takuissu Nguemto Guy, Azantsa Kingue Boris Gabin, J. L. Ngondi and Gouado Innocent
  
  Postprandial hyperglycemia and oxidative stress are implicated in the pathophysiology of type 2 diabetes. An alternative treatment should target both conditions. The present study aimed to evaluate the antioxidant and postprandial glucose-lowering potential of a polyphenolic rich extract of Nypa fruticans nuts. Hydroethanolic extract (HEE) was prepared; polyphenol and fl avonoid content was determined. In vitro antioxidant activity was done through molybdenum (VI) reduction and ABTS and DPPH radical-scavenging capacities. The glucose-lowering potential of the extract was evaluated through in vitro glucose-binding capacity, the regulatory ability of the extract on the pancreas of normal Wistar rats (oral glucose tolerance test), and digestion of carbohydrates (starch and sucrose) by normal Wistar rats. Starch (1 g/kg of the body weight (BW) and sucrose (2 g/kg BW) solution were used as.. View More»
  DOI: 10.4172/0974-8369.1000407

  Abstract PDF