Journal of Carcinogenesis & Mutagenesis

Grzegorz Dyduch

Publications

• Research Article
  Cervical Intraepithelial Neoplasia-Predictive Molecular Growth Factors in Natural History
  Author(s): Robert Jach, Bartlomiej Galarowicz, Klaudia Stangiel-Wójcikiewicz, Tomasz Banas, Joanna Streb, Artur Ludwin, Inga Ludwin and Grzegorz DyduchRobert Jach, Bartlomiej Galarowicz, Klaudia Stangiel-Wójcikiewicz, Tomasz Banas, Joanna Streb, Artur Ludwin, Inga Ludwin and Grzegorz Dyduch
  
  There is considerable controversy regarding the possible over-treatment of patients with mild Cervical Intraepithelial Neoplasia (CIN), with lesions being often excised or ablated. Thus, identifying the markers of potentially malignant lesions would be of a great prognostic value. In the current study, we hypothesized that using colposcopic, cytological and histological findings together with assessing the expression of molecular growth factors can predict CIN outcome. The study group consisted of 285 women between 19 and 81 years of age (median age, 37,8 years). The follow up were 60 months and considered 138 women: 50 women with Subclinical Papillomavirus Infection (SPI), 50 women with CIN1 and 38 women with CIN2.  All patients underwent cytology, colposcopy, and sampling for subsequent testing for HPV. In cases in which colposcopy suggested the presence of suspicious lesions, .. View More»
  DOI: 10.4172/2157-2518.S2-003

  Abstract PDF