Journal of Aquaculture Research & Development

Emad A Hashish

Publications

• Research Article
  Protective Effects of Selenium and Alpha-Tocopherol against Lead-Induced Hepatic and Renal Toxicity in Oreochromis Niloticus
  Author(s): Shimaa A Elgaml,Ryad Khalil,Emad A Hashish,Abdelhakeem El-MurrShimaa A Elgaml,Ryad Khalil,Emad A Hashish,Abdelhakeem El-Murr
  
  Lead is a serious poison causing serious injury or death. Current study was designed to investigate the potential protective effect of selenium (Se) and alpha-tocopherol (alpha-toc) against the hepatic and renal toxicity of lead acetate in Oreochromis niloticus. Two hundred and twenty five O. niloticus were divided into five groups; control, lead acetate treated (73.40 mg/liter), Se treated (4 mg sodium selenite/ kg diet), alpha-toc treated (200 mg/kg diet) plus Se + alpha-toc co-treated groups for 10 weeks. Levels of aspartate aminotransferase (AST), alanine transaminase (ALT), total protein, urea, creatinine, calcium (Ca), inorganic phosphate (P), magnesium (Mg), superoxide dismutase (SOD), reduced glutathione (GSH) and the lipid peroxidation index (MDA) were determined The results revealed an increase in the levels of liver enzymes, urea, creatinine and MDA; meanwhile, the total pr.. View More»
  DOI: 10.4172/2155-9546.1000299

  Abstract PDF