Dilip K Nandi
PG Department of Human Physiology, Raja Narendra Lal. Khan Women’s College (Autonomous),
Midnapore-721102, West Bengal
India
Research Article
Protective Role of Green Synthesized Gold Nanoparticles Using Terminalia arjuna against Acetaminophen Induced Hematological Alterations in Male Wistar Rats
Author(s): Mousumi Mitra, Amit Bandyopadhyay, Gouriprasad Datta and Dilip K NandiMousumi Mitra, Amit Bandyopadhyay, Gouriprasad Datta and Dilip K Nandi
Background: The present study aim to investigate on the characterization of green synthesized gold nanoparticles (AuNPs) and to evaluate whether this herbal nanoparticle can increase the efficiency of herb for alteration of hematological indices against acetaminophen induced toxicity in male Wistar rats.
Methods: Bark extract of Terminalia arjuna was used for the green synthesis of AuNPs and then characterization of the nanoparticles were done. Then experiment was conducted on 24 healthy male Wistar rats. The animals were divided into four groups, each group having six rats. Group-1: Control; Group- 2: acetaminophen treated (500 mg / kg) for 14 days; Group-3: Co-administration of acetaminophen (500 mg/kg/day) along with Terminalia arjuna bark extract (175 μg/kg/day) for 14 days; Group-4: Co-administration acetaminophen (.. View More»
DOI:
10.35248/2157-7439.19.10.530