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Ashraf Zedan
Ashraf Zedan
Egypt
Publications
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Research Article
The Role of Anti-Helicobacter Pylori Therapy in Remission Induction of Primary Gastric Lymphoma by Analysis of Microsatellite Instability
Author(s): Azza M Ezz Eldin, Enas Reda Alkareemy, Ashraf Zedan, Ahmed Abdel Warith, Amen H. Zaky and A KhalifaAzza M Ezz Eldin, Enas Reda Alkareemy, Ashraf Zedan, Ahmed Abdel Warith, Amen H. Zaky and A Khalifa
Background: The molecular mechanism associated with remission of primary gastric lymphoma post helicobacter pylori eradication is still unclear. Aim of the study: to evaluate Microsatellite (MSI) instability at markers adjacent to Chromosomal loci involved in primary gastric lymphoma in relation to helicobacter eradication therapy. Methods: 107 primary gastric lymphoma patients included 30 low grade Mucosa Associated Lymphoid Tissue Gastric lymphoma (MALT), 36 Diffuse large gastric lymphoma with MALT component (MALTDLBCL) and 41 DLBCL gastric lymphoma (DLBCL) were treated with anti Helicobacter pylori therapy as fi rst line treatment and to asses for Microsatellite instability (MSI) Results: the incidence of complete remissio.. View More»
DOI: 10.4172/2157-2518.1000107