Ammarin T
Thailand
Research Article
Cost Benefit Analysis of Prenatal Screening Test with Thai NIPT (Thai Non- Invasive Prenatal Test) for Down Syndrome in Developing Countries
Author(s): Oraluck P, Boonsong O, Wasun C, Ammarin T and Panyu POraluck P, Boonsong O, Wasun C, Ammarin T and Panyu P
Objective: The purpose of this study was to assess cost benefits of prenatal screening test for Down syndrome in developing countries (like Thailand) in order to inform OB/GYN clinical practice and medical/public health policy). Methods: A decision tree model was developed to analyze cost-benefits of the two screening modalities versus conventional screening test as base case. The first screening modality was universal Thai NIPT (Thai Non-invasive Prenatal Test) and the second was contingent Thai NIPT. Input parameters related to clinical values and costs were obtained from both primary and secondary sources for Thai population. One-way analysis and probabilistic sensitivity analysis were performed to evaluate uncertainty surrounding model parameters. Results: Based on the societal perspective, performing universal Thai NIPT and contingent Thai NIPT yielded differences of incremental .. View More»
DOI:
10.4172/2375-4273.1000207