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Ali Hussein A
Ali Hussein A
Kenya
Publications
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Research Article
HER2/Neu Protein Over-Expression in Patients with Gastric and Gastro- Esophageal Junction Carcinoma Seen at Kenyatta National Hospital, Kenya
Author(s): Ali Hussein A, Rogena Emily, Omulo TM and Ndaguatha PLWAli Hussein A, Rogena Emily, Omulo TM and Ndaguatha PLW
Background: Gastric cancer in Kenya is ranked third in both males and females. Most patients present clinically with advanced unsusceptible disease have poor prognosis despite administration of standard chemotherapy. Human epidermal growth factor receptor–2 (HER-2) over expression in gastric cancer is related to poor outcome. Advances in molecular therapy, have identified HER-2 to be an important component in the treatment of advanced gastric cancer. The prevalence of HER-2 in Kenya is unknown. Objective: To determine the prevalence of HER-2 overexpression in patients with gastric and gastro-oesophageal junction carcinoma at Kenyatta National Hospital. Methodology: Descriptive Cross sectional study on patients with histological diagnosis from endoscopic/resection specimens of gastric or GEJ cancer at KNH. A sampl.. View More»
DOI: 10.4172/2157-2518.1000186