Indexed In
- Open J Gate
- Genamics JournalSeek
- CiteFactor
- Cosmos IF
- Scimago
- Ulrich's Periodicals Directory
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- Directory of Abstract Indexing for Journals
- OCLC- WorldCat
- Proquest Summons
- Scholarsteer
- ROAD
- Virtual Library of Biology (vifabio)
- Publons
- Geneva Foundation for Medical Education and Research
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Abstract
Current Knowledge Regarding the Biological Methods of Assessing DNA Damage in Humans
This work summarizes the information available currently regarding the biological methods of assessing DNA (Deoxyribonucleic Acid) damage in humans. The methods include the comet assay (for determining single-strand DNA breaks, alkali-labile sites, and cross-links), the micronucleus assay, cytogenetic assays (which include the sister chromatid exchange assay and chromosomal aberration assay), oxidative DNA damage assays (including the measurement of oxidized bases like 8-oxo-7, 8-dihydro-2'-deoxyguanosine), and DNA repair assays. However, selecting the best method will depend on a number of factors, including the study's objectives, the type of DNA damage being measured, the resources at hand, and the study's size. A more comprehensive understanding of DNA damage and its potential effects on human health may also result from combining different techniques. Assay standardization and continuous technological advancements will enhance our ability to accurately assess DNA damage in humans.
Published Date: 2024-03-05; Received Date: 2024-01-02