Journal of Blood Disorders & Transfusion

The effect of Taraxacum officinale hydro alcoholic extract on blood cells in mice

3^rd International Conference on Hematology & Blood Disorders

November 02-04, 2015 Atlanta, USA

Mehrdad Modaresi

Islamic Azad University, Iran

Posters-Accepted Abstracts: J Blood Disord Transfus

Abstract:

Taraxacum officinale, the common dandelion is herbaceous perennial plant of the family Asteraceae. Dandelion has both medicinal and culinary uses. Dandelion has been used as remedy for anemia; purify the blood and immune modulation. Therefore the aim of this study was to investigate the effect of hydro alcoholic extract on blood cells in mice. Five groups each including ten adult female (Balb/C) mice weighing 30±5 g was chosen. Normal saline was administered as placebo for group and dandelion hydro alcoholic extract in doses of 50, 100, 200 mg/kg was injected intraperitoneally for 20 days o test groups and the last group was control group. WBC, RBC, HB, HCT, Platelet and other cells were measured with automated cell counter. The number of RBC and the rate of HB in three doses of 50, 100 and 200 mg/kg significantly increased (p<0.05). As compared with control group, the number of WBC in three doses of 50, 100 and 200 mg/kg increased but it was significantly in 200 mg/kg dandelion treated group as compared with control group (p<0.05). The rate of platelet in three doses of 50, 100 and 200 mg/kg significantly decreased as compared with control group (p<0.01). The study indicates efficacy of dandelion extract on RBC and HB in doses of 50, 100, 200 mg/kg and in 200 mg/kg on WBC to achieve normal body balance.

Biography :

Email: mehrdad_modaresi@hotmail.com