Journal of Blood Disorders & Transfusion

Surface enhanced Raman scattering with gold nanoparticles on exosomes

2^nd International Conference on Hematology & Blood Disorders

September 29-October 01, 2014 DoubleTree by Hilton Baltimore-BWI Airport, USA

Furong Tian

Accepted Abstracts: J Blood Disorders Transf

Abstract:

Exosomes can potentially be used for prognosis, therapy, and biomarkers for health and disease. Surface Enhanced Raman Scattering (SERS) by gold nanoparticles has been explored extensively for applications in sensing and imaging of exosomes. Resent results show the star shaped particle can enhance RAMAN signal such as exosome. Not like the gold spherical particle shows the SPR at lmax~560 nm. The gold nano star has an absorbance spectrum which is broad peaked, from ~600 nm and ~700 nm. Those peaks derive from the two constituent structures of the nanostar, the spherical core and the peripheral vertices. The spherical core results in a SPR similar to the nanospheres while the multiple vertices contribute SPR in the near infrared range. The optical properties of the those gold star in suspension thus reflect the characteristics of the local fields associated with the SPR. Thenanostars, the sharp vertices similarly act as local field hotspots resulting in SPRs shifted to the near infrared region of the spectrum.