SPECTROPHOTOMETRIC DATA IN THE INTERACTIONS BETWEEN HUMAN IMMUNODEFICIENCY VIRUS (HIV) AND BLOOD CELLS TREATED WITH ANTIRETROVIRAL DRUGS
8th World Congress on Healthcare & Medical Tourism
November 17-18, 2016 | Dubai UAE

Okwuchukwu Ani, Adaeze Ani

Enugu State University of Science and Technology, Nigeria
Chukwuemeka Odumegwu Ojukwu University, Nigeria

Posters & Accepted Abstracts: Health Care: Current Reviews

Abstract:

A synergy between engineers and biological researchers may obviously be needed so as to achieve a more reliable research result. The spectrophotometric data in the interactions between the Human immunodeficiency virus (HIV) and blood cells treated with antiretroviral drug were collected to be used to show the effects of antiretroviral drugs on the absorbance characteristics of HIV infected and uninfected blood. The methodology involved the serial dilution of the five different antiretroviral drugs (two HAART/FDC and three single drugs) and the subsequent incubation with the blood samples collected from ten HIV infected persons that had not yet commenced treatment with the antiretroviral drugs, ten HIV infected persons that had already commenced treatment with the antiretroviral drugs and ten HIV negative persons, for the absorbance measurements using a digital Ultraviolet Visible MetaSpecAE1405031Pro Spectrophotometer. The peak absorbance data for various interacting systems were measured. These were used to show that the antiretroviral drug has the effect of increasing the peak absorbance values of both the infected and uninfected blood components, that is, the drugs are made able to increase the light absorption capacity of the blood cells. The use of the findings of this work in drug design by pharmaceutical industries may be expected to yield good results.

Biography :

Email: okwyenoch@yahoo.com