Journal of Blood Disorders & Transfusion

Safety of intratechal chemotherapy in the management of hematological malignancies

3^rd International Conference on Hematology & Blood Disorders

November 02-04, 2015 Atlanta, USA

Javier Pardo Moreno

Universidad Rey Juan Carlos, Spain

Posters-Accepted Abstracts: J Blood Disord Transfus

Abstract:

Treatment of leptomeningeal metastasis (LMD) remains challenging due to advanced systemic disease at presentation and limited treatment options. Intratechal chemotherapy is one of the options actually used. Besides the hematological malignancies, the prophylactic use of this procedure is common in some entities. Unless, there is no complete knowledge of the toxicity and security of this practice, different factors could influence in the presence or not of adverse events. These factors could be the way of administration (ommaya reservoir or lumbar puncture), the presence or not of disease (prophylaxis or treatment), the drug we use (triple therapy or liposomal cytarabine or metrothrexate), the type of malignancy (lymphoma, leukemia or myeloma). It is necessary to know all these features with the aim of checking the security of a procedure that nowadays is a common alternative of treatment of a serious complication of hematological malignancies.

Biography :

Email: javier.pardo@hospitalreyjuancarlos.es