Journal of Bacteriology & Parasitology

Resistance pattern of locally isolated Escherichia coli of clinical origin against commonly isolated used antibiotics

6^th International Congress on Bacteriology & Infectious Diseases

May 21-22, 2018 | New York, USA

Shumaila Naz Malik and Faisal Iqbal Afridi

Jinnah University for women Karachi, Pakistan
Ziaudine University Hospital Karachi, Pakistan

Posters & Accepted Abstracts: J Bacteriol Parasitol

Abstract:

Introduction: E. coli is normal flora of intestine and most common enteric organism, but virulent strain of E. coli are involved in many infection like gastroenteritis and urinary tract infection. The main purpose of this study to evaluate the resistance profile of the clinical isolates of E. coli, as the increasing resistant to antibiotics creating problem in the disease treatment. For this aspect we tried to find out the existing antimicrobial agent that can use to treat infection related to E. coli. Method: A total 70 strains of E. coli from different diagnostic laboratories and hospital in the periods of January to July 2016. The sensitivity of testing of common antibiotics was analyzed by using disc diffusion method. This study revealed that all the isolates of E.coli were sensitive to imepenem (100%) followed by tazobactem/pipercillin, amikacin and gentaicin that were 60.7%, 44.44% and 43.33%. On other hand, these organisms are highly resistant to nalidixic acid, cefuroxime and trimethoprim/ sulphamethoxazole that were 73.3%, 83.3% and 86.6%. Result: It can be interpreted that the drug of choice in the study is Imipenem, but they can also be treated with amikacin and gentamicine. The increase use of resistant to antibiotics can cause the emergence of new resistance strains. So there is need to have a tightly regulated system of antibiotic prescription and also need of few antibiotic discoveries for the betterment in the health care industry. sho.malik-14@hotmail.com