Journal of Bioequivalence & Bioavailability

Psychoactive indole alkaloids in higher fungi: New species and perspectives

2^nd International Conference & Expo on Biopharmaceutics and Biologic Drugs

September 14-16, 2016 San Antonio, USA

Jochen Gartz

Fungi Enterprise, Germany

Posters & Accepted Abstracts: J Bioequiv Availab

Abstract:

Sixty years ago, R.G. Wasson discovered an ancient cult in Mexico R.Heim classified the species in the genus Psilocybe. A.Hofmann published the isolation and synthesis of the psychoactive alkaloids psilocybin and psilocin. We discovered two new species in 1994. The unusually large and potent Psilocybe azurescens was found in the Pacific Northwest ,U.S.A..Psilocybe natalensis was the first psychoactive species ever discovered in South Africa. Additionally, we have published Psilocybe germanica as a new, wood -loving species from Germany in 2015. These mushrooms were differentiated from the other psychoactive species growing on wood chips.too. All collections differ in the amounts of indole alkaloids including the precursor of psilocybin,baeocystin.Psychoactive mushrooms from other genera have been reported with increasing frequency in last decades. The trimethylammonium analog of psilocybin (aeruginascin ) has only been reported in the hallucinogenic species Inocybe aeruginascens . Additionally, we found biotransformations of synthetic tryptamine derivatives in mycelial cultures of Psilocybe. These investigations should achieve new applications in biological research and medicine.

Biography :

Email: g6888244@primacom.net