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Protein domain analysis from genomic sequence data revealed the regulation of LRR related domains in plant transpiration in Ficus
4th World Congress on Bioavailability and Bioequivalence: Pharmaceutical R&D Summit
May 20-22, 2013 DoubleTree by Hilton, Beijing, China
Tiange Lang, Jinyu Liu, Kunfang Cao and Charles H. Cannon
Scientific Tracks Abstracts: J Bioequiv Availab
Abstract:
W e developed a pipeline which can predict protein domains directly from genomic sequence data without a reference genome. The pipeline avoided some complex problems of de novo assembly such as micro reads and small single repeats. We used the pipeline on Ficus genomic data and found that the combination of LRRNT_2 and LRR_8 domains is related to hydrophobic process in Ficus. From the view of protein sequence, all those domains have leucine-rich repeats where leucine is a hydrophobic amino acid