Journal of Bacteriology & Parasitology

Prevalence of Staphylococcus aureus associated with multi-drug resistance in some hospitals in Limbe Health District in the South West Region of Cameroon

International Conference on Parasitology

August 24-26, 2015 Philadelphia, USA

Arrey Eyong Emmanuel and Lorenzo Eladnyuke Ewunkem

University of Buea, Cameroon

Posters-Accepted Abstracts: J Bacteriol Parasitol

Abstract:

Nosocomial and community-acquired Staphylococcus aureus infections are significant burdens to our health care systems. These infections are associated with significant morbidity and mortality, increased length of hospitalization and increase treatment costs. A study on Staphylococcus aureus was carried out with a view to isolating, determining the prevalence and antibiotic sensitivity pattern of the isolates present in clinical and environmental samples in Limbe Health District. The results obtained indicated that 231 samples examined (104 environmental, 102 from patients and 25 from health workers), 85(36.8%) were positive for Staphylococcus aureus. Fifty three (41.7%) and thirty-two (30.8%) represented positive cases from clinical and environmental samples respectively. Of the clinical samples examined, gentile secretions (68.2%) had the highest isolation rate while furniture had the highest isolation rate (40.6%) of S. aureus in environmental samples. Females were more predisposed to infection as well as individuals of the age group 31-40years. Results of antibiotic sensitivity tests carried out showed that vancomycin was most effective (100% susceptible) closely followed by ofloxacin (71.8% susceptible). Isolates exhibited complete resistance (100%) to ampcillin, bacitacin and penicillin. Marked resistance was also observed in methicitin (94.1% resistance), gentamicin (83.5% resistance) and oxacillin (75.3% resistance). Twenty-one antibiotyes were identified. A composite biochemical-antimicrobial profile revealed five biotypes (I, II, III, IV and V) with biotype I being the most frequently encountered, biotype II had the highest occurrence of seven antibiotypes while biotypes IV and V had the least number of antiobiotypes (two each). The multiple resistances observed are not surprising as multi-drug resistant strains are steady increasing over the years. As such, hospital infection control strategies will have to be redefined and community approaches developed to reduce transmission.

Biography :

Email: arrey_eyong@yahoo.com