Journal of Bacteriology & Parasitology

Prevalence of blaNDM-1-producing Escherichia coli in Asia: A systematic review and meta-analysis

7^th International Conference on Bacteriology and Infectious Diseases

June 04-05, 2018 Osaka, Japan

Masoud Dadashi, Bahareh Hajikhani, Parviz Owlia, Ramin PourIran and Ali Hashemi

Shahid Beheshti University of Medical Sciences, Iran
Baqiyatallah University of Medical Sciences, Iran

Posters & Accepted Abstracts: J Bacteriol Parasitol

Abstract:

Background & Aim: NDM-1 gene (blaNDM-1)-producing Escherichia coli is allegedly perceived as one of the most indispensable multidrug-resistant bacteria causing infections in hospitals and clinic domains. In numerous Asian countries, sporadic studies have been conducted to investigate the prevalence of blaNDM-1-producing E. coli. The nobility of the present study was to determine the precise prevalence of blaNDM-1-producing E. coli in different parts of Asia indeed. Methods: Several international databases including Medline, Embase and Web of sciences were searched from March 2005 to Jan 2016 to discern studies addressed the prevalence of blaNDM-1-producing E. coli in Asia. Comprehensive meta-analysis (V2.2, Biostat) software was used to interpret the data. Results: Of the 588 records identified from the databases, 15 studies fulfilled the eligibility criteria ostensibly. The analyses manifested that the prevalence of blaNDM--producing E. coli was 30.7% [95% confidence interval (95% CI) 16.2-50.2] in the analyzed Asian countries. Hence, the further stratified analyses indicated that the prevalence of blaNDM-1-producing E. coli was higher in the probes, particularly after 2010. Conclusion: It was magnificently attained that the relatively high prevalence of blaNDM-1-producing E. coli merit in our analysis. Moreover, regular surveillance for hospital associated infection, monitoring antibiotic sensitivity pattern, and formulation of definite antibiotic policies advocates viable roles for prevention and control of blaNDM-1-producing E. coli certainly. Masoud.dadashi@sbmu.ac.ir