Journal of Bacteriology & Parasitology

Prevalence and sensitivity pattern of urinary pathogens in childrenâ??s medical center in Iran, compared to England (2007-2008)

3^rd International Congress on Bacteriology and Infectious Diseases

August 04-06, 2015 Valencia, Spain

Elham Azizi and Seyed Taher Esfahani

Posters-Accepted Abstracts: J Bacteriol Parasitol

Abstract:

Objective: This study was performed to determine uropathogens in Children’s Medical Center and their sensitivity to antibiotics.
Methods: A retrospective cross sectional data review was carried out on 130 records of children aged>2 months admitted
between 2007-2008 in Children’s Medical Center in Iran and results were compared with a study done in this center in 1999-
2000. To achieve to more lucrative conclusion we have demonstrated results of a study in England about UTI, comparing two
periods (1996 and 2000).
Findings: Prevalence of uropathogens in PMC in both of the periods (1999-2000 vs. 2007-2008) was as follows: E. coli (81%,
58.5%), Klebsiella (5% and 15.4%), Pseudomonas (5% and 10%), Enterococcus (0% and 7.7%), Enterobacter (2% and 4.6%),
Proteus (2% and 1.5%), S. aureus (0%, 3%), Candida (0%, 1%). In the 1999-2000 years the sensitivity of causative agents of
UTI to the Cephalosporins group was remarkable (Ceftizoxime 83.6% and Ceftriaxone 81.4%) but in the 2007-2008 years the
sensitivity of UTI agents to the Cephalosporins has decreased and the Aminoglycosides group attending Nitrofurantoin have
outclassed the Cephalosporins.
Conclusion: Predominant causative agent in CMC is E. coli, but prevalence of other causative agents is increasing. Uropathogens
are becoming resistant gradually to common antibiotics. We suggest aminoglycosides as best choice for empiric treatment of
UTI. Sensitivity of uropathogens to antibiotics in our center is lower than the center in England.