Journal of Microbial & Biochemical Technology

Phytochemical screening and antimicrobial activity of some marketed herbal preparations against clinical isolate of Salmonella Typhi

International Conference and Summit on Industrial & Pharmaceutical Microbiology

October 17-18, 2016 Kuala Lumpur, Malaysia

Hajara Muhammed Ladan

Ahmadu Bello University, Nigeria

Posters & Accepted Abstracts: J Microb Biochem Technol

Abstract:

Technology based scientific research in herbal medicine perhaps has some significant impact in addressing some prominent doubts about herbal preparations such as packaging problems, level of hygiene and dosage regimen. Various laboratory researches have been extensively carried out to screen the efficacy of traditional concoction generally against several causative agents of diseases in vitro and in vivo which gave significant result. One of such research worth of note is that against Salmonella Typhi. Laboratory experiments were conducted to screen out five different mixtures of herbal preparations against clinical isolates of Salmonella Typhi in vitro. The preparations were extracted using water and ethanol as solvent. Extracts were subjected to phytochemical screening and antimicrobial activity on clinical isolates of Salmonella spp. The phytochemical screening indicated the presence of carbohydrates, glycosides, saponins, steroids, triterpenes, tannins, flavonoids and alkaloids. The aqueous extract was much inhibitory to the test isolates with activity observed in all the five mixtures of the herbal preparations, while the ethanol extracts of two mixtures showed inhibition against the test isolate. The minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) of the aqueous extract were found to fall within the range concentration of 18.75 mg/ml and 37.5 mg/ml while that of ethanol extract was at the range of 9.375 mg and 37.5 mg/ ml. It is therefore concluded that the herbal preparations have great potentials as source of remedy against typhoid fever and other forms of salmonellosis.

Biography :

Email: ummunauwar@gmail.com