Journal of Pharmacovigilance

Personalized Medicine (PM) as national and international models of healthcare services of the newest generation: A green light towards the innovations to secure biopharma and translational resources

11^th International Conference and Exhibition on Pharmacovigilance & Drug Safety

June 21-22, 2018 | London, UK

Sergey Suchkov, Jeff Skolnick, Mariya Studneva, Marc Hendrikx, Paul Barach and Arsenii Sadykov

Sechenov University, USA

Posters & Accepted Abstracts: J Pharmacovigil

Abstract:

A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized medicine (PM). To achieve the implementation of PM concept into the daily practice including clinical cardiology, it is necessary to create a fundamentally new strategy based upon the subclinical recognition of bioindicators (biopredictors and biomarkers) of hidden abnormalities long before the disease clinically manifests itself. Each decision-maker values the impact of their decision to use PM on their own budget and well-being, which may not necessarily be optimal for society as a whole. It would be extremely useful to integrate data harvesting from different databanks for applications such as prediction and personalization of further treatment to thus provide more tailored measures for the patients and persons-at-risk resulting in improved outcomes whilst securing the healthy state and wellness, reduced adverse events, and more cost effective use of health care resources. One of the most advanced areas in cardiology is atherosclerosis, cardiovascular and coronary disorders as well as in yocarditis. A lack of medical guidelines has been identified by the majority of responders as the predominant barrier for adoption, indicating a need for the development of best practices and guidelines to support the implementation of PM into the daily practice of cardiologists! Implementation of PM requires a lot before the current model �??physician-patient�?� could be gradually displaced by a new model �??medical advisor-healthy person-at-risk�?�. This is the reason for developing global scientific, clinical, social, and educational projects in the area of PM to elicit the content of The new branch. �?� T.A. Bodrova, D.S. Kostyushev, E.N. Antonova, Sh. Slavin, D.A. Gnatenko, M.O. Bocharova, M. Legg, P. Pozzilli, S.V.. Suchkov. Introduction into PPPM as a new paradigm of public health service: an integrative view EPMA Journal, 2012, 3, 16, P. 3-16 �?� Sergey Suchkov. Predictive, Preventive and Personalized Medicine (PPPM) as an integrative part of national healthcare services to move ahead In: Proceedings (Programme Book) of the ESBB Annual Meeting, Verona, Italy, October 8th-11th, 2013, P. 30-31, S-13 �?� I.A. Sadkovsky, O. Golubnitschaja, M.A. Mandrik, M.A. Studne-va1, H. Abe, H. Schroeder, E.N. Antono-va, F.Betsou, T.A. Bodrova, K. Payne, S.V. Suchkov. PPPM (Predictive, Preventive and Personalized Medicine) as a New Model of the National and International Healthcare Services and Thus a Promising Strategy to Prevent a Disease: From Basics to Practice. International Journal of Clinical Medicine, 2014, 5, 855-870 �?� Zemskov VM, Alekseev AA, Gnatenko DA, Kozlova MN, Shishkina NS, Zemskov AM, Zhegalova IV, Bleykhman DA, Bahov NI, Suchkov SV. Overexpression of Nitric Oxide Synthase Re-stores Circulating Angiogenic Cell Function in Patients With Coronary Artery Disease: Implications for Autologous Cell Therapy for Myocardial Infarction. The Journal of the American Heart Association, 2016, 5, 1-18 �?� Zemskov, A., Zemskov, V., Zemskova, V., Buch, T., Cherno-va, L. Bleykhman, D., Marshall, T., Abe, H., Zhegalova, I., Barach, P. and Suchkov, S. A STEPWISE SCREENING PROTOCOL TO SECURE THE MODULE-BASED TREATMENT FOR MANAGING IMMUNOPATHOLOGY. International Journal of Information Research and Review, 2017, Vol. 04, Issue, 01, pp. 3507-3510.