Journal of Bacteriology & Parasitology

Parasitic and bacterial infections in patients at Qinghai University Affiliated Hospital in Xining, Tibetan Plateau in Qinghai Province, China

2^nd International Conference on Parasitology

August 01-03, 2016 Manchester, UK

Panagiotis Karanis, Gabriele Karanis, Anna Ronge, Oliver Schell, Chuan Lu and Dechun Li

Qinghai University, China
University of Cologne, Germany
Qinghai University Affiliated Hospital, China

Posters & Accepted Abstracts: J Bacteriol Parasitol

Abstract:

The present survey investigated patients hospitalized in the Qinghai University Affiliated Hospital (QUAH) in Xining, Tibetan Plateau of Qinghai Province, Northwest of China. Two studies were designed to find out, if unexpected and not-detected pathogens could be found in fecal samples and other body fluids from Chinese diarrheal patients: The samples were investigated for the presence of Cryptosporidium and Giardia infections since these pathogens and parasites in general were not included in the hospital laboratory�??s routine microbiological screening program. Giardia: 5 (4 stool, 1 sputum sample, generated from 3 patients) of 143 samples have been found to be positive by IFT, from which 2 have been highly positive. 11 stool samples have been found to be positive by nested PCR based on SSU rRNA, 2 based on TPI and 1 based on GDH gene. In microscopically analyzed body fluids no Giardia cysts have been found as expected, except for one sputum sample by IFT. By sequencing, 4 of these samples have been determined as Giardia intestinalis assemblage B. Cryptosporidium: 6 out of 143 samples, which are 1 sputum and 5 stool samples, were found to be positive by IFT, two out of these six positive samples are also positive by m-ZN. 2 samples have been positive by n-PCR based on SSU rRNA and two others based on TRAP C2. One case of double-infection with Giardia and Cryptosporidium was special because of the presence of Giardia in sputum. The third part presents the case study of extra pulmonary tuberculosis (epTB) of the shoulder joint of a 49 years old man, pointing out that tuberculosis often remains undetected even in a country known as second high risk country for TB worldwide. In the present case report, delayed anti-TB treatment has led to serious destruction of the shoulder joint. Physical disability, accompanied by depression, unemployment and social decline are the consequences. Early and clear diagnosis of epTB, adequate management and therapy in Q-T Plateau area still need improvement and the government�??s attention.

Biography :

Panagiotis Karanis has obtained his PhD in Parasitology from Bonn University following Post-doctoral research activities in Germany, Greece, Australia, Japan, Canada, Thailand and China, he has been working in the field of medical, epidemiological and molecular parasitology taken into account both the pathogen and the disease. His worldwide research activities focused in the control of water-borne and vector-borne parasitic diseases including the development of diagnostic assays useful for basic and clinical platforms in the field of biomedicine. He was the main speaker of the Nobel-Days-Lecture during the Nobel-Days-Festivities at the Orebro University in Sweden in December 10th, 2012, focused on malaria vaccine development.

Email: panagiotis.karanis@uk-koeln.de