Journal of Bioequivalence & Bioavailability

Optimizing formulation to maximize drug absorption from solution formulations

6^th World Congress on Bioavailability & Bioequivalence: BA/BE Studies Summit

August 17-19, 2015 Chicago, USA

Wenzhan Yang

Scientific Tracks Abstracts: J Bioequiv Availab

Abstract:

Solution formulations are not all made equal. The type of excipients as well as the level of excipients in solutions can have either positive or negative impact on oral
absorption of drug molecules. In this presentation, considerations and evaluation tools in selecting and optimizing solution formulations in order to maximize the oral
absorption of drug molecules will be illustrated with case studies.

Biography :

Wenzhan Yang holds a PhD degree in Pharmaceutical Science. She has experiences in both academia and pharmaceutical industries. She has been with AstraZeneca for
about 10 years. She has worked on projects from preclinical stage through commercial products. Her current focus is on compound selection to support both infection and
oncology projects from preclinical to first time in man. Her publications focuses mainly on delivering poorly soluble drugs by solubilization as well as drug delivery systems.
Her research interests are in the area of solubilization, nanoparticles and targeted delivery.