Health Care : Current Reviews

NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN AS AN EARLY MARKER FOR THE DIAGNOSIS OF URINARY TRACT INFECTIONS IN SAUDI CHILDREN

8^th World Congress on Healthcare & Medical Tourism

November 17-18, 2016 | Dubai UAE

Khalid M Baghdadi, Waleed M Toffaha, Ghazi M Sindi

King Abdulaziz University, Saudi Arabia

Posters & Accepted Abstracts: Health Care: Current Reviews

Abstract:

Background: Urinary Tract Infection (UTI) are widespread infections in the pediatric age group with non-specific symptoms. �??Neutrophil gelatinase-associated lipocalin�?� (NGEL) is a biomarker in determining kidney injury. The early urinary tract infections diagnosis is essential for the purpose of preventing unwanted consequences. Aim: To evaluate the use of (NGAL) as an early predictor of UTI in clinical practice. Patients and methods: A cross-sectional study examined specificity and sensitivity of urinary NGAL I the early UTI diagnosis. All febrile children admitted to KAAUH (age:0-14 years) were included. Mann-Whitney U test, Shapiro-Wilk�??s test, and spearman correlation was used to analyze the data. Results: In terms of mean urinary NGAL, no significant difference was observed between urinary NGAL levels in patients with and without UTI (P-value = 0.17). The reserve operator characteristic curve demonstrated 0.594 sensitivity, and 0.683 specificity. For serum CRP (ROC) curve demonstrated 0.53 sensitivity and 0.47 specificity. Spearman�??s correlation was undertaken to examined un association between NGAL and CRP level. There was a positive monotonic correlation between NGAL and CRP level (rs = 0.503 n = 73, p < 0.001). Conclusion: Urinary NGAL is a poor biomarker for the diagnosis of febrile UTI. Further investigations are required with a larger group of patients to confirm the results of this study.

Biography :

Khalid Mohammed Baghdadi is currently a medical intern in King Abdulaziz University hospital. He was born and raised in the city of Jeddah on the west coast of Saudi Arabia. Throughout his school years he sought excellence in his journey to enter the school of medicine, and he graduated from high school as the first of his class in 2010. He participated in many extra curricular activities during his college life including research activities, awareness campaigns and volunteering work aiming to help younger medical students. He graduated from medical school in 2016 with first honors and is aiming to continue his medical career in diagnostic radiology.

Email: kmb1992@gmail.com