Journal of Bacteriology & Parasitology

Microsporidial keratitis in immunocompetent patients from a tertiary care Centre of North India

International Conference on Parasitology

August 24-26, 2015 Philadelphia, USA

Sonu Kumari Agrawal, Sumeeta Khurana, Kirti Megha, R Sehgal and Amit Gupta

Postgraduate Institute of Medical Education and Research, India

Posters-Accepted Abstracts: J Bacteriol Parasitol

Abstract:

Keratitis is a second leading cause of blindness in both developing and developed countries after cataract. Various microorganisms such as bacteria, fungi, viruses and parasites can cause keratitis. Parasitic corneal pathogens viz. Onchocerca, Leishmania, Trypanosoma, Acanthamoeba, have been well described with recent attention focused on microsporidial keratitis. At present, microsporidial keratitis is under-diagnosed and under-reported and early diagnosis is essential for better management. A total of 260 patients with suspected infectious keratitis presenting to the Advanced Eye Centre at Postgraduate Institute of Medical Education and Research, a tertiary care Centre of North India were included. Their corneal scrapings and tear samples were collected for microscopic examination and molecular diagnosis. A total of 2 patients (0.76%) were diagnosed with microsporidial keratitis by Calcofluor white and Modified trichrome staining and one sample (0.38%) by PCR. Both the patients had history of mud/soil exposure and trauma with vegetative matter. Both cases presented with recurrent keratitis of seven to eight months duration with non-healing epithelial defect and deep stromal infiltrate. One patient underwent corneal transplant while other did not turn up for follow up. Thus, microsporidial keratitis should be considered in differential diagnosis of keratitis especially following trauma to eye.

Biography :

Sonu kumari Agrawal is currently pursuing M.D in Microbiology from Department of Medical Microbiology, Postgraduate Institute of Medical Education, and Research, Chandigarh, India. She received Infectious diseases certificate course (IDCC) from P.D. Hinduja hospital, Mumbai and also best oral presentation award in “TROPACON 2013 (Gold medal)”.

Email: dr.sonu1986@gmail.com