Journal of Allergy & Therapy

Investigating the possible effect of oral magnesium on the improvement of sudden sensorineural hearing loss: A clinical trial study

9^th International Conference on Otology, Rhinology and Laryngology

November 10, 2023 | Webinar

Mohammad Taha Mehdi -Araghi

Shahid Beheshti University of Medical Sciences, Iran

Accepted Abstracts: J Allergy Ther

Abstract:

Sudden Sensorineural Hearing Lloss (SSNHL), involves the rapid and unexplained loss of hearing that occurs over several days or permanently. Various studies are trying to add a safe supplement or drug to speed up the healing process in patients. In this study, we aimed to investigate the effect of adding oral magnesium on hearing changes in patients with sudden sensorineural hearing loss. Material and Methods: SSNHL patients were randomly divided into two groups of magnesium and placebo. The intervention group was magnesium (given oral corticosteroids (1 mg / kg / day) prednisone and 250 mg magnesium oxide capsules for 10 days) and the placebo group (receiving oral cortisone prednisone (1 mg / kg / day) for 10 days and placebo (32 people in each group). At the beginning of the study, audiometry of patients was performed. Between 10 and 30 days after the treatment protocols, audiometry was performed again to evaluate the therapeutic effect and the changes were evaluated and compared. Results: The mean age of patients was 46.64 ±10.72 years. There was no significant difference between the two groups in terms of gender distribution and ear involvement (P = 0.57). The rate of hearing loss in the right ear and hearing loss in both the control and experimental groups showed an improvement over 30 days, however, the improvement in the intervention group showed a better improvement than the control group (P<0.05). Conclusion: The recovery trend was significant in placebo patients and oral magnesium patients in both groups. Oral magnesium in combination with oral corticosteroids further improved the hearing status of patients with sudden sensorineural hearing loss, but what is certain is that a more detailed study is needed to make a definitive statement.