Journal of Allergy & Therapy

Immunotherapy for atopic dermatitis as the causative treatment

7^th International Conference on Allergy, Asthma and Clinical Immunology

September 14-15, 2016 Amsterdam, Netherlands

Geunwoong Noh

Jeju Halla General Hospital, South Korea

Posters & Accepted Abstracts: J Allergy Ther

Abstract:

Atopic dermatitis is the eczematous skin allergic disease which is currently the issue to be solved. Until now, the nature of atopic dermatitis is not completely understood concerning the pathogenesis and the cause. Accordingly, the effective treatment for atopic dermatitis has not done. More than 10 years ago, food allergy is reported to be the important cause of atopic dermatitis. Interestingly, the nature of food allergy in atopic dermatitis is non-IgE mediated allergy in which skin prick test and specific IgE for the causative food allergens were negative. From this report, the nature of atopic dermatitis became unveiled. The nature of atopic dermatitis is non-IgE mediated allergy to food and inhalant allergens. Tolerance induction for food allergy of non-IgE mediated type in atopic dermatitis was successful using IFN-gamma. Also, desensitization for inhalant allergens also was succeeded using IFN-gamma. From both treatments, the concept of the causative diagnosis and treatment for atopic dermatitis become the real. With the success of tolerance induction for food allergy of non-IgE-mediated type and desensitization for inhalant allergens using IFN-gamma, the pathogenesis and nature of atopic dermatitis become clearer. Moreover, the pathogenesis of allergy becomes more clarified. Most of all, the difference of food and inhalant allergens in the role and the pathogenesis in atopic dermatitis become suspected. The architecture of the pathogenesis of atopic dermatitis is reconstructed on the base of clinical and immunological study.

Biography :

Email: admyth@naver.com